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PYRUVATE KINASE
Descriptors Found:
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DeCS
Descriptor
English
:
Pyruvate Kinase
Descriptor
Spanish
:
Piruvato Quinasa
Descriptor
Portuguese
:
Piruvato Quinase
Tree Number:
D08.811.913.696.620.695
Definition
English
:
ATP:
pyruvate
2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the
phosphorylation
of
pyruvate
to
phosphoenolpyruvate
in the presence of ATP. It has four
isozymes
(L, R, M1, and M2). Deficiency of the enzyme results in hemolytic
anemia
. EC 2.7.1.40.
Indexing Annotation
English
:
do not coord L-, R-, M-, M1- or M2-type
pyruvate kinase
with
ISOENZYMES
See Related
English
:
Anemia, Hemolytic
History Note
English
:
65
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
12207
Unique Identifier:
D011770
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS